Low-Pressure Chromatography Column
Low-pressure chromatography columns are pressure compressible glass columns designed for hygienic operation and simple, efficient loading, primarily for process development or biopharmaceutical production.
We have two types for the column. Smaller ones are manual packing for small testings. Bigger ones are automatic packing for industrial purification.
Manual Packing Column
- Cover all diameter
- Customization is available
- Patent column head sealing technology
- The lever-pressing sealing structure was used with high reliability, which prevents the problem that the pneumatic mechanism easy to leak and invalid
- The expansion structure of pressurizing-down style gasket ring prevents column head departing from bed caused by the pull-up structure
- Minimized Hold-up Volumes, Easy to clean and change the seal
- Patent column head rotating structure
- The column head rotates by the rotating screw of the column pipe, which is on the upper surface of the Flange plate After rotating in place, the second screw needs to be inserted. Media packing can be done after rotating the column head. It is easy to operate, without carrying out the column head
- Predictable linear scale-up
- Fix condition: Linear flow rate, buffer, packing material, bed height, sample concentration, and pH, sample volume, and bed volume ratio
- Scale-up condition: Column I.D., volume flow rate, sample volume
Column Parameters
| Product | Column Inner Diameter (mm) | Column Height (mm) | Packing Height (cm) | Pressure (≤bar) | Net Weight (kg) |
| MPC70/500 | 70 | 500 | 0-35 | 8 | 14 |
| MPC70/750 | 70 | 950 | 20-60 | 8 | 18 |
| MPC100/500 | 100 | 500 | 0-35 | 8 | 17 |
| MPC100/750 | 100 | 750 | 20-60 | 8 | 20 |
| MPC100/950 | 100 | 950 | 40-80 | 8 | 22 |
| MPC140/500 | 140 | 500 | 0-35 | 6 | 25 |
| MPC140/750 | 140 | 750 | 20-60 | 6 | 28 |
| MPC140/950 | 140 | 950 | 40-80 | 6 | 30 |
| MPC200/500 | 200 | 500 | 0-35 | 6 | 36 |
| MPC200/750 | 200 | 750 | 20-60 | 6 | 39 |
| MPC200/950 | 200 | 950 | 40-80 | 6 | 42 |
| MPC300/500 | 300 | 500 | 0-35 | 4 | 66 |
| MPC300/750 | 300 | 750 | 20-60 | 4 | 71 |
| MPC300/950 | 300 | 950 | 40-80 | 4 | 75 |
| MPC450/500 | 450 | 500 | 0-32 | 4 | 200 |
| MPC450/75 | 450 | 750 | 20-57 | 4 | 215 |
| MPC450/1000 | 450 | 1000 | 40-82 | 4 | 230 |
Automatic Packing Glass Column
- Intelligent Packing process
- Pump, Valves, Touch Screen, and Framework
- All operations could be done on Touch Screen
- Using the wizard to maintain, pack and unpack the column, avoiding mistakes
- The endpoint of packing is determined by sensors, and repeatability is excellent
- Simple
- Packing Station use pneumatic diaphragm valves to control every flow path independently, and easy to clean
- Patented Distributor
- Using fluid dynamics simulation to predict distributor performance
- The maximal column is 1200mm
- Customization is available
- Patented Tube Rotation Structure
- Special structure, easy operation, and reliable
- Loosen screws on the bottom of the column, the tube can be lifted up and rotated avoiding damage from misoperation
Column Parameters
| Product | Column Inner Diameter (mm) | Column Height (mm) | Packing Height (cm) | Pressure (≤bar) | Net Weight (kg) |
| APC 300/600 | 300 | 600 | 5-47 | 4 | 430 |
| APC 300/950 | 300 | 950 | 5-82 | 4 | 450 |
| APC 400/600 | 400 | 600 | 5-47 | 4 | 480 |
| APC 400/950 | 400 | 950 | 5-82 | 4 | 510 |
| APC 450/600 | 450 | 600 | 5-47 | 4 | 750 |
| APC 450/950 | 450 | 950 | 5-82 | 4 | 800 |
| APC 600/600 | 600 | 600 | 5-47 | 4 | 900 |
| APC 600/950 | 600 | 950 | 5-82 | 4 | 970 |
| APC 800/600 | 800 | 600 | 5-47 | 4 | 2100 |
| APC 800/950 | 800 | 950 | 5-82 | 4 | 2200 |
| APC 1000/600 | 1000 | 600 | 5-47 | 4 | 2700 |
| APC 1000/950 | 1000 | 950 | 5-82 | 4 | 2850 |
| APC 1200/600 | 1200 | 600 | 5-47 | 4 | 4800 |
| APC 1200/950 | 1200 | 950 | 5-82 | 4 | 5100 |
