Use Galaksil® C8 To Purify Insulin
Insulin is the only hormone in the body that can directly lower blood glucose. It can also stimulate the synthesis of glycogen, fat, and protein, and is the main drug used to treat diabetes.
Purification is a very important process in the whole production process. Galaksil® C8 silica gel chromatography resin has the advantages of low metal content, good pressure resistance of particles, and long lifetime, which make it suitable for insulin purification.
Column: C8 8μm 10×250mm
| Time | A | B |
| 0 | 85% | 15% |
| 5min | 85% | 15% |
| 15min | 64% | 36% |
| 225min | 34% | 66% |
| Galaksil® C8 | Cycle | Injection | Purification | P1 | P1c | P2 |
| 1 | 100ml | 99.76% | 0.21% | 0.02% | 0.01% | |
| 50ml | 99.74% | 0.22% | 0.02% | 0.02% | ||
| 2 | 50ml | 99.75% | 0.22% | 0.02% | 0.01% | |
| 3 | 50ml | 99.74% | 0.22% | 0.02% | 0.01% | |
| 4 | 50ml | 99.74% | 0.22% | 0.02% | 0.01% | |
| 5 | 50ml | 99.76% | 0.21% | 0.02% | 0.01% | |
| 6 | 50ml | 99.75% | 0.22% | 0.02% | 0.02% | |
| 7 | 50ml | 99.76% | 0.21% | 0.02% | 0.02% | |
| 8 | 50ml | 99.74% | 0.22% | 0.02% | 0.01% | |
| 9 | 50ml | 99.74% | 0.22% | 0.02% | 0.02% |
Galaksil® C8 silica-gel chromatography resin can be cycled several times with no change in purity, demonstrating that it is stable enough to be used for large-scale preparative production.
Related Products
Galaksil® C8 Silica-gel
Galaksil® HPLC Column